We describe a case of neuro-Behçet disease diagnosed in a 12-year-old girl. This patient presented with recurrent oral ulcers, incontinence, spastic gait, blurry vision, and asymmetrical lower extremity hypertonia. Extensive testing revealed punctate lesions through the central nervous system, vitritis, papillitis, and uveitis. A thorough infectious and neoplastic workup was negative. She was t...

OBJECTIVE To investigate the association of the 2 intracellular adhesion molecules-1 (ICAM-1) gene polymorphisms [thymidine/cytidine (T/C) 469 and guanosine/adenosine (G/A) 241] in Behçets disease in Lebanon. METHODS We initiated the study in July 2003, and carried out the work in the research laboratory of Beirut Arab University, Beirut, Lebanon. We extracted the DNA by glass fiber matrix mi...

“Neuro-Sweet disease (NSD)” was proposed as a distinct entity of encephalomeningitis in 1999 (1). Sweet disease has been considered as a multisystem inflammatory disorder characterized by painful erythematous plaques, and has been classified as a dermatologic disease. The plaques respond to systemic corticosteroids, and heal without scarring. It has been disclosed that aseptic neutrophilic infl...

Neuro-inflammation is a growing concern that is the result of nervous tissue inflammation. Some common causes that induce this problem are toxic metabolites, aging, autoimmunity, air pollution, et cetera. Glial cells and a group of proteins which are called cytokines are associated in neuro-inflammation. Some nervous diseases such as: Parkinson's disease, Alzheimer's disease and Multiple Sclero...